FILE NO. TLC-PI-NWK
Principal Investigator
Richard Wedeen , MD
Principal Investigator, Newark Clinical Center — UMDNJ / New Jersey Medical School
- Site
- Newark
- Affiliation
- University of Medicine & Dentistry of New Jersey + Newark VA
- TLC era
- 1990s
- Tags
- Principal InvestigatorLead NephrotoxicitySteering Committee
Lead nephrotoxicity researcher. Wedeen's expertise was in the renal effects of chronic lead exposure — distinct from the neurodevelopmental focus of the TLC primary outcome — which exemplifies a broader gap between the investigators' collective expertise in lead toxicity and the trial's narrow focus on cognitive endpoints.
Co-Principal Investigator at the Newark clinical site (UMDNJ + Newark VA Medical Center). TLC Steering and Publication Committee member.
Newark was one of four clinical sites; site-level differences in enrollment demographics, environmental lead exposure, and dust lead levels are central to the site-heterogeneity question.